1. What are adaptogens?
Adaptogens are plants and mushrooms that exert distinct effects on the mind and body, helping them be resilient to environmental, physical, mental and emotional stressors!
Some adaptogens do this by interacting with the HPA axis (hypothalamic-pituitary-adrenal axis), that controls the interaction and balance of hormones — including cortisol, a primary “stress hormone”.
Did you know?
Their effects help to both modulate the extent of the stress response – and help recover from it!
2. Why are they called adaptogens?
Because they help the body to physiologically “adapt” to stressful situations by working to maintain “homeostasis” or systemic equilibrium (balance).
When the systems of the body are working in balance and harmony – its resiliency is at its strongest – whether it be immunity, metabolism, or ability to cognitively and emotionally cope in stressful situations.
3. What is the history of adaptogens?
In 1947, the term “adaptogen” was proposed by a Swedish scientist in describing substances that appeared to support the body’s resistance against stress and promoted performance. Research was conducted at the Siberian Academy of Sciences looking for a more sustainable drug for the Soviets to replace amphetamines that could cause harm when used over time. But their tradition use as a tonic for vitality and resilience goes back thousands of years.
There is evidence of adaptogen use of herbs among may healing traditions: in Ayurvedic medicine: TCM, reishi and in Russian healing traditions. A few examples include:
There is evidence of adaptogen use of herbs among may healing traditions: in Ayurvedic medicine: TCM, reishi and in Russian healing traditions. A few examples include:
- Ashwagandha: A revered herb in traditional Ayurvedic medicine, used to enhance physical strength, improve energy levels, and reduce stress. Ancient Ayurvedic texts, such as the Charaka Samhita, mention Ashwagandha as a Rasayana, a rejuvenative that promotes longevity and vitality.
- Astragalus: A prominent adaptogen in Traditional Chinese Medicine (TCM), where it is called huang qi, which translates to “yellow life energy,” referring to the vibrant colour of its root, and its effects on vitality and longevity. Read more: Hello Herb! Herbal Spotlight: Astragalus - St. Francis Herb Farm
- Reishi: Another TCM staple, this mushroom is sometimes referred to as the “mushroom of immortality” and its interaction with the HPA axis is suggested to help reduce anxiety, support restful sleep, immunomodulation and improve mood.
- Rhodiola: Growing in the cold, mountainous regions of Europe and Asia, this hearty plant has been called “the original adaptogen” and has shown some profound benefits for mental and cognitive health.

Did you know?
Fun fact: The tenacious nature of adaptogens reflects their benefits. They tend to be very resilient plants that can grow even in inhospitable conditions! Some grow in extreme heat, and some in extreme cold.
4. Are there different types of adaptogens?
Yes! Primary and secondary adaptogens. The criteria for primary adaptogens include:
- Producing a Nonspecific Defense Response to Stress
- Exerting a Normalizing Influence on the Body
- Being Non-Toxic
- Calibrating endocrine, nervous system, immune, digestive, and cardiovascular function
Secondary adaptogens must possess some of these criteria. Also, different adaptogenic plants and mushrooms can be especially beneficial for certain facets of health! Some examples include:
- Ashwagandha – stress
- Astragalus - immunity
- Lion’s Mane – mood and cognition
Also, some adaptogens can be beneficial for sleep, while others can be energizing.
5. What is the best way to take adaptogens?
Adaptogens can be taken on a daily basis and can even be combined and taken together. However, when taking an adaptogen longer term, it is recommended that they be taken on a rotating regimen: 3 weeks on, 1 week off. This helps for maintaining the efficacy of the adaptogenic herbs and supporting the body’s ability to calibrate.
Pro Tip: Some adaptogenic herbs are perfectly safe for kids to use – including astragalus and codonopsis: both found in our Deep Immune® Kids products!
St. Francis Herb Farms Adaptogen Formulas
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Strest®
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Strest® Capsules
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Deep Immune®
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Allergy Relief with Deep Immune®
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Ashwagandha Capsules
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Reishi Mushroom
$49.99 -
Rhodiola
From: $25.49
References:
Marina Davydov, A.D. Krikorian, Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (Araliaceae) as an adaptogen: a closer look. Journal of Ethnopharmacology, Volume 72, Issue 3, 2000, Pages 345-393,ISSN 0378-8741, Retrieved from: https://doi.org/10.1016/S0378-8741(00)00181-1
Park HJ, Kim HY, Yoon KH, Kim KS, Shim I. The Effects of Astragalus Membranaceus on Repeated Restraint Stress-induced Biochemical and Behavioral Responses. Korean J Physiol Pharmacol. 2009 Aug;13(4):315-9. doi: 10.4196/kjpp.2009.13.4.315. Epub 2009 Aug 31. PMID: 19885016; PMCID: PMC2766712. Retrieved from: The Effects of Astragalus Membranaceus on Repeated Restraint Stress-induced Biochemical and Behavioral Responses - PMC
Todorova V, Ivanov K, Delattre C, Nalbantova V, Karcheva-Bahchevanska D, Ivanova S. Plant Adaptogens-History and Future Perspectives. Nutrients. 2021 Aug 20;13(8):2861. doi: 10.3390/nu13082861. PMID: 34445021; PMCID: PMC8398443. Retrieved from: Plant Adaptogens—History and Future Perspectives - PMC









